node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXG88585.1 | cmk | HMPREF3232_01487 | HMPREF3232_00339 | MazG family protein; KEGG: amc:MADE_1004050 1.4e-37 MazG protein; K04765 ATP diphosphatase; Psort location: Cytoplasmic, score: 7.50. | Cytidylate kinase; KEGG: ols:Olsu_0916 2.2e-101 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97. | 0.820 |
KXG88585.1 | coaX | HMPREF3232_01487 | HMPREF3232_00969 | MazG family protein; KEGG: amc:MADE_1004050 1.4e-37 MazG protein; K04765 ATP diphosphatase; Psort location: Cytoplasmic, score: 7.50. | Putative pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.779 |
KXG89405.1 | KXG90826.1 | HMPREF3232_00972 | HMPREF3232_00331 | KEGG: ols:Olsu_0102 1.2e-15 hypothetical protein; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.549 |
KXG89405.1 | coaD | HMPREF3232_00972 | HMPREF3232_00422 | KEGG: ols:Olsu_0102 1.2e-15 hypothetical protein; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.499 |
KXG89405.1 | coaX | HMPREF3232_00972 | HMPREF3232_00969 | KEGG: ols:Olsu_0102 1.2e-15 hypothetical protein; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Putative pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.421 |
KXG89405.1 | panC | HMPREF3232_00972 | HMPREF3232_00968 | KEGG: ols:Olsu_0102 1.2e-15 hypothetical protein; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.607 |
KXG90826.1 | KXG89405.1 | HMPREF3232_00331 | HMPREF3232_00972 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | KEGG: ols:Olsu_0102 1.2e-15 hypothetical protein; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | 0.549 |
KXG90826.1 | cmk | HMPREF3232_00331 | HMPREF3232_00339 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Cytidylate kinase; KEGG: ols:Olsu_0916 2.2e-101 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97. | 0.577 |
KXG90826.1 | coaD | HMPREF3232_00331 | HMPREF3232_00422 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.957 |
KXG90826.1 | coaX | HMPREF3232_00331 | HMPREF3232_00969 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.948 |
KXG90826.1 | panC | HMPREF3232_00331 | HMPREF3232_00968 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.917 |
KXG90826.1 | tmk | HMPREF3232_00331 | HMPREF3232_01186 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.557 |
atpH | coaX | HMPREF3232_00957 | HMPREF3232_00969 | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | Putative pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.400 |
cmk | KXG88585.1 | HMPREF3232_00339 | HMPREF3232_01487 | Cytidylate kinase; KEGG: ols:Olsu_0916 2.2e-101 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97. | MazG family protein; KEGG: amc:MADE_1004050 1.4e-37 MazG protein; K04765 ATP diphosphatase; Psort location: Cytoplasmic, score: 7.50. | 0.820 |
cmk | KXG90826.1 | HMPREF3232_00339 | HMPREF3232_00331 | Cytidylate kinase; KEGG: ols:Olsu_0916 2.2e-101 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.577 |
cmk | coaX | HMPREF3232_00339 | HMPREF3232_00969 | Cytidylate kinase; KEGG: ols:Olsu_0916 2.2e-101 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97. | Putative pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.472 |
cmk | panC | HMPREF3232_00339 | HMPREF3232_00968 | Cytidylate kinase; KEGG: ols:Olsu_0916 2.2e-101 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.923 |
cmk | tmk | HMPREF3232_00339 | HMPREF3232_01186 | Cytidylate kinase; KEGG: ols:Olsu_0916 2.2e-101 cytidylate kinase; Psort location: Cytoplasmic, score: 9.97. | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.445 |
coaD | KXG89405.1 | HMPREF3232_00422 | HMPREF3232_00972 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | KEGG: ols:Olsu_0102 1.2e-15 hypothetical protein; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase. | 0.499 |
coaD | KXG90826.1 | HMPREF3232_00422 | HMPREF3232_00331 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.957 |