node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KXG88513.1 | KXG88514.1 | HMPREF3232_01407 | HMPREF3232_01408 | Putative replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.989 |
KXG88513.1 | KXG91404.1 | HMPREF3232_01407 | HMPREF3232_00002 | Putative replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | CRISPR-associated endoribonuclease Cas2; KEGG: brm:Bmur_2247 5.3e-20 DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | 0.478 |
KXG88513.1 | dnaX | HMPREF3232_01407 | HMPREF3232_01462 | Putative replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.450 |
KXG88513.1 | polA | HMPREF3232_01407 | HMPREF3232_00588 | Putative replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.578 |
KXG88514.1 | KXG88513.1 | HMPREF3232_01408 | HMPREF3232_01407 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.989 |
KXG88514.1 | KXG88875.1 | HMPREF3232_01408 | HMPREF3232_01185 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: ols:Olsu_1445 3.5e-62 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | 0.989 |
KXG88514.1 | KXG89408.1 | HMPREF3232_01408 | HMPREF3232_00975 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; KEGG: apv:Apar_0110 4.2e-107 exodeoxyribonuclease III Xth K01142; Psort location: Cytoplasmic, score: 9.97. | 0.984 |
KXG88514.1 | KXG89425.1 | HMPREF3232_01408 | HMPREF3232_00992 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ImpB/MucB/SamB family protein; KEGG: cgo:Corgl_0698 6.5e-102 DNA-directed DNA polymerase K03502; Psort location: Cytoplasmic, score: 7.50. | 0.995 |
KXG88514.1 | KXG89577.1 | HMPREF3232_01408 | HMPREF3232_00851 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: ols:Olsu_0701 0. DNA polymerase III subunit alpha; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97. | 0.989 |
KXG88514.1 | KXG91318.1 | HMPREF3232_01408 | HMPREF3232_00056 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: ols:Olsu_0981 7.1e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 7.50. | 0.992 |
KXG88514.1 | KXG91351.1 | HMPREF3232_01408 | HMPREF3232_00089 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: mkm:Mkms_3999 0.0021 integral membrane sensor signal transduction histidine kinase; K02484 two-component system, OmpR family, sensor kinase; Psort location: Cytoplasmic, score: 7.50. | 0.990 |
KXG88514.1 | KXG91404.1 | HMPREF3232_01408 | HMPREF3232_00002 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | CRISPR-associated endoribonuclease Cas2; KEGG: brm:Bmur_2247 5.3e-20 DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | 0.983 |
KXG88514.1 | dnaX | HMPREF3232_01408 | HMPREF3232_01462 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.993 |
KXG88514.1 | polA | HMPREF3232_01408 | HMPREF3232_00588 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
KXG88875.1 | KXG88514.1 | HMPREF3232_01185 | HMPREF3232_01408 | KEGG: ols:Olsu_1445 3.5e-62 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.989 |
KXG88875.1 | KXG89577.1 | HMPREF3232_01185 | HMPREF3232_00851 | KEGG: ols:Olsu_1445 3.5e-62 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | KEGG: ols:Olsu_0701 0. DNA polymerase III subunit alpha; K02337 DNA polymerase III subunit alpha; Psort location: Cytoplasmic, score: 9.97. | 0.981 |
KXG88875.1 | KXG91318.1 | HMPREF3232_01185 | HMPREF3232_00056 | KEGG: ols:Olsu_1445 3.5e-62 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | KEGG: ols:Olsu_0981 7.1e-41 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cytoplasmic, score: 7.50. | 0.990 |
KXG88875.1 | KXG91351.1 | HMPREF3232_01185 | HMPREF3232_00089 | KEGG: ols:Olsu_1445 3.5e-62 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: mkm:Mkms_3999 0.0021 integral membrane sensor signal transduction histidine kinase; K02484 two-component system, OmpR family, sensor kinase; Psort location: Cytoplasmic, score: 7.50. | 0.546 |
KXG88875.1 | KXG91404.1 | HMPREF3232_01185 | HMPREF3232_00002 | KEGG: ols:Olsu_1445 3.5e-62 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | CRISPR-associated endoribonuclease Cas2; KEGG: brm:Bmur_2247 5.3e-20 DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | 0.956 |
KXG88875.1 | dnaX | HMPREF3232_01185 | HMPREF3232_01462 | KEGG: ols:Olsu_1445 3.5e-62 DNA polymerase III, delta prime subunit K02341; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, subunit gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.958 |