| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KXG88514.1 | KXG88566.1 | HMPREF3232_01408 | HMPREF3232_01468 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | 0.823 |
| KXG88514.1 | KXG89408.1 | HMPREF3232_01408 | HMPREF3232_00975 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease III; KEGG: apv:Apar_0110 4.2e-107 exodeoxyribonuclease III Xth K01142; Psort location: Cytoplasmic, score: 9.97. | 0.950 |
| KXG88514.1 | KXG91086.1 | HMPREF3232_01408 | HMPREF3232_00192 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: ols:Olsu_0735 7.8e-232 exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50. | 0.912 |
| KXG88514.1 | KXG91404.1 | HMPREF3232_01408 | HMPREF3232_00002 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | CRISPR-associated endoribonuclease Cas2; KEGG: brm:Bmur_2247 5.3e-20 DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | 0.815 |
| KXG88514.1 | polA | HMPREF3232_01408 | HMPREF3232_00588 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.995 |
| KXG88514.1 | recR | HMPREF3232_01408 | HMPREF3232_01464 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.480 |
| KXG88565.1 | KXG88566.1 | HMPREF3232_01467 | HMPREF3232_01468 | HAD hydrolase, family IB; KEGG: mej:Q7A_31 1.7e-16 phosphoserine phosphatase; Psort location: CytoplasmicMembrane, score: 8.16. | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | 0.785 |
| KXG88566.1 | KXG88514.1 | HMPREF3232_01468 | HMPREF3232_01408 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.823 |
| KXG88566.1 | KXG88565.1 | HMPREF3232_01468 | HMPREF3232_01467 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | HAD hydrolase, family IB; KEGG: mej:Q7A_31 1.7e-16 phosphoserine phosphatase; Psort location: CytoplasmicMembrane, score: 8.16. | 0.785 |
| KXG88566.1 | KXG89408.1 | HMPREF3232_01468 | HMPREF3232_00975 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | Exodeoxyribonuclease III; KEGG: apv:Apar_0110 4.2e-107 exodeoxyribonuclease III Xth K01142; Psort location: Cytoplasmic, score: 9.97. | 0.945 |
| KXG88566.1 | KXG91086.1 | HMPREF3232_01468 | HMPREF3232_00192 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | KEGG: ols:Olsu_0735 7.8e-232 exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50. | 0.418 |
| KXG88566.1 | KXG91404.1 | HMPREF3232_01468 | HMPREF3232_00002 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | CRISPR-associated endoribonuclease Cas2; KEGG: brm:Bmur_2247 5.3e-20 DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97. | 0.467 |
| KXG88566.1 | ligA | HMPREF3232_01468 | HMPREF3232_00837 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | 0.434 |
| KXG88566.1 | mfd | HMPREF3232_01468 | HMPREF3232_01486 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.416 |
| KXG88566.1 | nth | HMPREF3232_01468 | HMPREF3232_01479 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.638 |
| KXG88566.1 | polA | HMPREF3232_01468 | HMPREF3232_00588 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.456 |
| KXG88566.1 | recR | HMPREF3232_01468 | HMPREF3232_01464 | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.465 |
| KXG89408.1 | KXG88514.1 | HMPREF3232_00975 | HMPREF3232_01408 | Exodeoxyribonuclease III; KEGG: apv:Apar_0110 4.2e-107 exodeoxyribonuclease III Xth K01142; Psort location: Cytoplasmic, score: 9.97. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.950 |
| KXG89408.1 | KXG88566.1 | HMPREF3232_00975 | HMPREF3232_01468 | Exodeoxyribonuclease III; KEGG: apv:Apar_0110 4.2e-107 exodeoxyribonuclease III Xth K01142; Psort location: Cytoplasmic, score: 9.97. | Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50. | 0.945 |
| KXG89408.1 | KXG91086.1 | HMPREF3232_00975 | HMPREF3232_00192 | Exodeoxyribonuclease III; KEGG: apv:Apar_0110 4.2e-107 exodeoxyribonuclease III Xth K01142; Psort location: Cytoplasmic, score: 9.97. | KEGG: ols:Olsu_0735 7.8e-232 exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50. | 0.491 |