STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (220 aa)    
Predicted Functional Partners:
KXG89408.1
Exodeoxyribonuclease III; KEGG: apv:Apar_0110 4.2e-107 exodeoxyribonuclease III Xth K01142; Psort location: Cytoplasmic, score: 9.97.
 
 0.997
KXG88566.1
Base excision DNA repair protein, HhH-GPD family; KEGG: apv:Apar_0121 5.4e-82 HhH-GPD family protein; K03575 A/G-specific adenine glycosylase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.829
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.814
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
  
 0.791
KXG91351.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: mkm:Mkms_3999 0.0021 integral membrane sensor signal transduction histidine kinase; K02484 two-component system, OmpR family, sensor kinase; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.633
KXG88502.1
DnaQ family exonuclease/DinG family helicase; KEGG: ols:Olsu_0005 2.3e-177 DNA polymerase III subunit epsilon K03722; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.626
mfd
Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.
 
   
 0.608
KXG91086.1
KEGG: ols:Olsu_0735 7.8e-232 exonuclease RecJ K07462; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.598
KXG91404.1
CRISPR-associated endoribonuclease Cas2; KEGG: brm:Bmur_2247 5.3e-20 DNA polymerase III subunit epsilon; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.540
KXG88576.1
Putative magnesium transporter; KEGG: pmt:PMT0126 4.2e-40 Mg2+ transporter K06213; Psort location: CytoplasmicMembrane, score: 10.00.
       0.504
Your Current Organism:
Atopobium vaginae
NCBI taxonomy Id: 82135
Other names: A. vaginae, ATCC BAA-55, ATCC:BAA 55, ATCC:BAA:55, CCUG 38953, CIP 106431, DSM 15829, NCTC 13935
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