STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFO63361.1O-acetylhomoserine sulfhydrylase. (428 aa)    
Predicted Functional Partners:
metAA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.989
MetH
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.967
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 
0.944
Bmt
5-methyltetrahydrofolate--homocysteine methyltransferase.
 
 
 0.934
SFO17663.1
Cystathione beta-lyase.
   
 0.929
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.921
SFO76606.1
Hypothetical protein.
      0.917
SFP01921.1
Cysteine synthase A.
 
 0.898
SFO68610.1
Homoserine dehydrogenase.
 
 
 0.891
SFO40463.1
Cysteine synthase A.
 
 0.870
Your Current Organism:
Paracoccus pantotrophus
NCBI taxonomy Id: 82367
Other names: ATCC 35512, DSM 2944, JCM 21485, LMD 82.5, NBRC 102493, NCCB 82005, P. pantotrophus, Thiosphaera pantotropha, strain GB 17, strain GB17
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