node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gltB_1 | ilvB1 | RS83_02999 | RS83_03211 | Glutamate synthase [NADPH] large chain. | Acetolactate synthase large subunit IlvB1. | 0.806 |
gltB_1 | ilvC | RS83_02999 | RS83_03209 | Glutamate synthase [NADPH] large chain. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.890 |
gltB_1 | ilvD_2 | RS83_02999 | RS83_03212 | Glutamate synthase [NADPH] large chain. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.813 |
gltB_1 | ilvE | RS83_02999 | RS83_03199 | Glutamate synthase [NADPH] large chain. | Branched-chain-amino-acid aminotransferase. | 0.530 |
gltB_1 | ilvH | RS83_02999 | RS83_03210 | Glutamate synthase [NADPH] large chain. | Putative acetolactate synthase small subunit. | 0.950 |
gltB_1 | leuA | RS83_02999 | RS83_02744 | Glutamate synthase [NADPH] large chain. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.578 |
gltB_1 | leuB | RS83_02999 | RS83_03200 | Glutamate synthase [NADPH] large chain. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.647 |
gltB_1 | leuC | RS83_02999 | RS83_03175 | Glutamate synthase [NADPH] large chain. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.832 |
gltB_1 | leuD | RS83_02999 | RS83_03174 | Glutamate synthase [NADPH] large chain. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.773 |
gltB_1 | pabC | RS83_02999 | RS83_02157 | Glutamate synthase [NADPH] large chain. | Aminodeoxychorismate lyase. | 0.530 |
ilvB1 | gltB_1 | RS83_03211 | RS83_02999 | Acetolactate synthase large subunit IlvB1. | Glutamate synthase [NADPH] large chain. | 0.806 |
ilvB1 | ilvC | RS83_03211 | RS83_03209 | Acetolactate synthase large subunit IlvB1. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.987 |
ilvB1 | ilvD_2 | RS83_03211 | RS83_03212 | Acetolactate synthase large subunit IlvB1. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.977 |
ilvB1 | ilvE | RS83_03211 | RS83_03199 | Acetolactate synthase large subunit IlvB1. | Branched-chain-amino-acid aminotransferase. | 0.754 |
ilvB1 | ilvH | RS83_03211 | RS83_03210 | Acetolactate synthase large subunit IlvB1. | Putative acetolactate synthase small subunit. | 0.995 |
ilvB1 | leuA | RS83_03211 | RS83_02744 | Acetolactate synthase large subunit IlvB1. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.685 |
ilvB1 | leuB | RS83_03211 | RS83_03200 | Acetolactate synthase large subunit IlvB1. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.738 |
ilvB1 | leuC | RS83_03211 | RS83_03175 | Acetolactate synthase large subunit IlvB1. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.744 |
ilvB1 | leuD | RS83_03211 | RS83_03174 | Acetolactate synthase large subunit IlvB1. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.742 |
ilvB1 | pabC | RS83_03211 | RS83_02157 | Acetolactate synthase large subunit IlvB1. | Aminodeoxychorismate lyase. | 0.645 |