Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dnaNDNA polymerase III, beta subunit; Pfam matches to PF02767.12 DNA_pol3_beta_2, and to PF00712.15 DNA_pol3_beta, and to PF02768.11 DNA_pol3_beta_3; draft locus tag CAMGR0001_0277. (359 aa)    
Predicted Functional Partners:
polA
DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 0.995
dnaX
DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.990
holA
DNA polymerase III, delta subunit; Draft locus tag CAMGR0001_1989.
    
 0.989
dnaE
DNA polymerase III, alpha subunit; Pfam matches to PF07733.8 DNA_pol3_alpha, and to PF02811.15 PHP, and to PF14579.2 HHH_6; draft locus tag CAMGR0001_0475.
    
 0.989
holB
DNA polymerase III, delta prime subunit; Pfam match to PF13177.2 DNA_pol3_delta2; draft locus tag CAMGR0001_1974.
 
 
 0.983
dinP
DNA polymerase IV; Pfam matches to PF00817.16 IMS, and to PF11799.4 IMS_C; draft locus tag CAMGR0001_1426.
   
 0.964
lig
DNA ligase; Pfam matches to PF14743.2 DNA_ligase_OB_2, and to PF01068.17 DNA_ligase_A_M; draft locus tag CAMGR0001_2022.
   
 0.961
gyrB
DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
 
 0.930
dnaQ
DNA polymerase III, epsilon subunit; Pfam match to PF00929.20 RNase_T; draft locus tag CAMGR0001_2825.
    
 0.928
xth
Exodeoxyribonuclease III (exonuclease III); Pfam match to PF03372.19 Exo_endo_phos; draft locus tag CAMGR0001_1575.
   
 0.926
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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