STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT91482.1Diguanylate cyclase/phosphodiesterase; Pfam matches to PF00563.16 EAL, and to PF00990.17 GGDEF; draft locus tag CAMGR0001_0279. (476 aa)    
Predicted Functional Partners:
AKT93538.1
Putative PAS sensor-containing diguanylate phosphodiesterase; Pfam matches to PF00563.16 EAL, and to PF00989.20 PAS; draft locus tag CAMGR0001_0214.
 
 
 0.988
AKT91821.1
PAS sensor-containing diguanylate cyclase/phosphodiesterase; Pfam matches to PF00990.17 GGDEF, and to PF00563.16 EAL, and to PF13426.2 PAS_9; draft locus tag CAMGR0001_2635.
 
 
 0.976
AKT91484.1
HD family hydrolase, possible ComGF family competence protein; Pfam match to PF13023.2 HD_3; draft locus tag CAMGR0001_0281.
       0.834
AKT91922.1
Two-component system sensor histidine kinase; Pfam matches to PF02518.22 HATPase_c, and to PF00072.20 Response_reg, and to PF00512.21 HisKA, and to PF08376.6 NIT; draft locus tag CAMGR0001_2504.
 
  
 0.828
gyrB
DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.805
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
       0.804
dnaN
DNA polymerase III, beta subunit; Pfam matches to PF02767.12 DNA_pol3_beta_2, and to PF00712.15 DNA_pol3_beta, and to PF02768.11 DNA_pol3_beta_3; draft locus tag CAMGR0001_0277.
       0.794
AKT91923.1
Two-component system response regulator; Pfam match to PF00072.20 Response_reg; draft locus tag CAMGR0001_2503.
  
  
 0.663
AKT92014.1
PAS sensor-containing two-component system histidine kinase; Pfam match to PF08447.7 PAS_3; draft locus tag CAMGR0001_1710.
 
 
 0.629
AKT93558.1
Transcriptional regulator, TetR family; Pfam match to PF00440.19 TetR_N; draft locus tag CAMGR0001_0245.
  
 
 0.620
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.