| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adk | apt | CGRAC_0993 | CGRAC_1106 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.936 |
| adk | guaB | CGRAC_0993 | CGRAC_0669 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.531 |
| adk | purB | CGRAC_0993 | CGRAC_0050 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Pfam matches to PF00206.16 Lyase_1, and to PF10397.5 ADSL_C; draft locus tag CAMGR0001_0342; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.942 |
| adk | surE | CGRAC_0993 | CGRAC_0418 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.916 |
| apt | adk | CGRAC_1106 | CGRAC_0993 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.936 |
| apt | guaB | CGRAC_1106 | CGRAC_0669 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.668 |
| apt | purA | CGRAC_1106 | CGRAC_0356 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.437 |
| apt | purB | CGRAC_1106 | CGRAC_0050 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Pfam matches to PF00206.16 Lyase_1, and to PF10397.5 ADSL_C; draft locus tag CAMGR0001_0342; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.949 |
| apt | purH | CGRAC_1106 | CGRAC_1401 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | AICAR transformylase / IMP cyclohydrolase; Bifunctional; Pfam matches to PF01808.14 AICARFT_IMPCHas, and to PF02142.18 MGS; draft locus tag CAMGR0001_1920. | 0.955 |
| apt | surE | CGRAC_1106 | CGRAC_0418 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.915 |
| argH | guaB | CGRAC_0095 | CGRAC_0669 | Pfam matches to PF00206.16 Lyase_1, and to PF14698.2 ASL_C2; draft locus tag CAMGR0001_0085. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.403 |
| argH | purB | CGRAC_0095 | CGRAC_0050 | Pfam matches to PF00206.16 Lyase_1, and to PF14698.2 ASL_C2; draft locus tag CAMGR0001_0085. | Pfam matches to PF00206.16 Lyase_1, and to PF10397.5 ADSL_C; draft locus tag CAMGR0001_0342; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.912 |
| guaB | adk | CGRAC_0669 | CGRAC_0993 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.531 |
| guaB | apt | CGRAC_0669 | CGRAC_1106 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.668 |
| guaB | argH | CGRAC_0669 | CGRAC_0095 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pfam matches to PF00206.16 Lyase_1, and to PF14698.2 ASL_C2; draft locus tag CAMGR0001_0085. | 0.403 |
| guaB | purA | CGRAC_0669 | CGRAC_0356 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.992 |
| guaB | purB | CGRAC_0669 | CGRAC_0050 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Pfam matches to PF00206.16 Lyase_1, and to PF10397.5 ADSL_C; draft locus tag CAMGR0001_0342; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.925 |
| guaB | purC | CGRAC_0669 | CGRAC_1301 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Pfam match to PF01259.14 SAICAR_synt; draft locus tag CAMGR0001_2341; Belongs to the SAICAR synthetase family. | 0.722 |
| guaB | purD | CGRAC_0669 | CGRAC_0097 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Phosphoribosylamine-glycine ligase; Pfam matches to PF01071.15 GARS_A, and to PF02844.11 GARS_N, and to PF02843.12 GARS_C; draft locus tag CAMGR0001_0081; Belongs to the GARS family. | 0.699 |
| guaB | purF | CGRAC_0669 | CGRAC_0278 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.837 |