STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas2aCRISPR/Cas system-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (90 aa)    
Predicted Functional Partners:
cas1a
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.998
cas1b
CRISPR/Cas system-associated endonuclease Cas1, type I-B/HMARI; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.919
cas4
CRISPR/Cas system-associated RecB-like nuclease Cas4, type I-B/HMARI; Pfam match to PF01930.13 Cas_Cas4; draft locus tag CAMGR0001_2371.
 
 
 
 0.871
cas6a
CRISPR/Cas system-associated RAMP protein Cas6, type III; Pfam match to PF10040.5 DUF2276; draft locus tag CAMGR0001_0358.
 
   
 0.856
cas10
CRISPR/Cas system-associated RAMP protein Cas10, type III-A/MTUBE; Draft locus tag CAMGR0001_1747.
 
   
 0.698
csm3
CRISPR/Cas system-associated RAMP protein Csm3, type III-A/MTUBE; Pfam match to PF03787.11 RAMPs; draft locus tag CAMGR0001_1749.
 
   
 0.670
AKT91545.1
Hypothetical protein; Draft locus tag CAMGR0001_0118.
 
   
 0.669
csm4
CRISPR/Cas system-associated RAMP protein Csm4, type III-A/MTUBE; Draft locus tag CAMGR0001_1750.
 
   
 0.446
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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