STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqnD1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. (298 aa)    
Predicted Functional Partners:
mqnC
Dehypoxanthinylfutalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
  
 0.979
ubiA
4-hydroxybenzoate octaprenyltransferase; Pfam match to PF01040.14 UbiA; draft locus tag CAMGR0001_2671; Belongs to the UbiA prenyltransferase family.
 
   
 0.801
mqnE
Menaquinone biosynthesis protein, SCO4494 family; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
 
   
 0.782
mqnA2
6-amino-6-deoxyfutalosine synthase; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.711
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Pfam match to PF01977.12 UbiD; draft locus tag CAMGR0001_1098; Belongs to the UbiD family.
  
   
 0.648
oorA
2-oxoglutarate:acceptor oxidoreductase, alpha subunit; Pfam match to PF01855.15 POR_N; draft locus tag CAMGR0001_0940.
     
  0.499
oorB
2-oxoglutarate:acceptor oxidoreductase, beta subunit; Pfam match to PF02775.17 TPP_enzyme_C; draft locus tag CAMGR0001_0939.
     
  0.499
oorC
2-oxoglutarate:acceptor oxidoreductase, gamma subunit; Pfam match to PF01558.14 POR; draft locus tag CAMGR0001_0938.
     
  0.499
mfrB
Methylmenaquinol:fumarate reductase, MfrB subunit; Pfam matches to PF13085.2 Fer2_3, and to PF13183.2 Fer4_8; draft locus tag CAMGR0001_0883.
     
  0.499
recA
Recombinase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
       0.482
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.