STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemDUroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (210 aa)    
Predicted Functional Partners:
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.988
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.933
hemB
Porphobilinogen synthase; Pfam match to PF00490.17 ALAD; draft locus tag CAMGR0001_1808; Belongs to the ALAD family.
  
 
 0.839
moaE
Molybdopterin synthase, large subunit; Pfam match to PF02391.13 MoaE; draft locus tag CAMGR0001_1856.
  
    0.821
ftsX
Cell division protein FtsX; Draft locus tag CAMGR0001_1547.
 
     0.789
AKT91601.1
Tetratricopeptide repeat protein; Pfam match to PF13432.2 TPR_16; draft locus tag CAMGR0001_0038.
 
     0.787
lptD
Putative lipooligosaccharide transport system, OM component (LptD family); Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
     0.781
lptA
Putative lipooligosaccharide transport system, periplasmic component (LptA family); Pfam match to PF03968.10 OstA; draft locus tag CAMGR0001_2360.
  
   
 0.774
AKT91894.1
Putative lipooligosaccharide transport system, permease component (LptG family); Pfam match to PF03739.10 YjgP_YjgQ; draft locus tag CAMGR0001_2542.
  
     0.772
AKT92456.1
Mechanosensitive ion channel family protein; Pfam match to PF00924.14 MS_channel; draft locus tag CAMGR0001_1125.
 
     0.770
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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