STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (308 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase, bacterial type; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.985
ilvD
Dihydroxyacid dehydratase; Pfam match to PF00920.17 ILVD_EDD; draft locus tag CAMGR0001_0185; Belongs to the IlvD/Edd family.
  
 0.974
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     
 0.911
ilvA
Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391.
  
 
 0.901
AKT92546.1
Putative membrane protein; Pfam match to PF04186.9 FxsA; draft locus tag CAMGR0001_0989.
     
  0.900
hom
Pfam matches to PF00742.15 Homoserine_dh, and to PF03447.12 NAD_binding_3, and to PF01842.21 ACT; draft locus tag CAMGR0001_2654.
  
 
 0.859
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.828
AKT91618.1
Prohibitin family protein, SPFH superfamily; Pfam match to PF01145.21 Band_7; draft locus tag CAMGR0001_0018.
  
    0.800
trpDG
Anthranilate phosphoribosyltransferase / anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
  
  
 0.598
hisIE
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; Bifunctional; Pfam matches to PF01502.14 PRA-CH, and to PF01503.13 PRA-PH; draft locus tag CAMGR0001_0015; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.590
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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