STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpXATP-dependent ClpXP protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (412 aa)    
Predicted Functional Partners:
clpP
ATP-dependent ClpAP/ClpXP protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 0.995
carB
Carbamoylphosphate synthase, large subunit; Pfam matches to PF02786.13 CPSase_L_D2, and to PF02786.13 CPSase_L_D2, and to PF02787.15 CPSase_L_D3, and to PF02142.18 MGS; draft locus tag CAMGR0001_2714; Belongs to the CarB family.
     
 0.838
lpxA
UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
     0.823
fabZ
3-hydroxyacyl-[acp] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
  
 0.817
mrdB
Cell wall shape-determining protein; Pfam match to PF06723.9 MreB_Mbl; draft locus tag CAMGR0001_2716.
   
 
 0.816
mreC
Rod shape-determining protein MreC; Pfam match to PF04085.10 MreC; draft locus tag CAMGR0001_2715.
     
 0.813
atpD
ATP synthase, F1 complex, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.
 
    
 0.776
msrAB
Bifunctional (RS)-methionine sulfoxide reductase A/B; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.743
queH
Putative protein (DUF208 domain); Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
       0.701
lon
DNA-binding, ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
 
 0.632
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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