STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
birAbiotin-[acetyl-CoA-carboxylase] ligase; Pfam match to PF03099.15 BPL_LplA_LipB; draft locus tag CAMGR0001_2608. (211 aa)    
Predicted Functional Partners:
bioB
Biotin synthetase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.932
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.923
pycA
Pyruvate carboxylase, subunit A; Pfam matches to PF02786.13 CPSase_L_D2, and to PF00289.18 CPSase_L_chain, and to PF02785.15 Biotin_carb_C; draft locus tag CAMGR0001_0759.
    
 0.915
parA
Chromosome partitioning protein; Pfam match to PF01656.19 CbiA; draft locus tag CAMGR0001_2607.
     
 0.823
parB
Chromosome partitioning protein; Pfam match to PF02195.14 ParBc; draft locus tag CAMGR0001_2606; Belongs to the ParB family.
  
  
 0.803
fmt
10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.800
AKT91840.1
Hypothetical protein; Draft locus tag CAMGR0001_2609.
       0.773
atpF-2
ATP synthase, F0 complex, b subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
 
     0.705
atpH
ATP synthase, F1 complex, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
 
     0.682
pycB
Pyruvate carboxylase, subunit B; Pfam matches to PF02436.14 PYC_OADA, and to PF00364.18 Biotin_lipoyl, and to PF00682.15 HMGL-like; draft locus tag CAMGR0001_0046.
   
 
 0.633
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.