STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisCHistidinol-phosphate aminotransferase; Pfam match to PF00155.17 Aminotran_1_2; draft locus tag CAMGR0001_2538; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase; Pfam match to PF00475.14 IGPD; draft locus tag CAMGR0001_2366.
 
 0.998
hisIE
phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphatase; Bifunctional; Pfam matches to PF01502.14 PRA-CH, and to PF01503.13 PRA-PH; draft locus tag CAMGR0001_0015; In the N-terminal section; belongs to the PRA-CH family.
 
  
 0.992
pheA
Chorismate mutase / prephenate dehydratase; Bifunctional; Pfam matches to PF00800.14 PDT, and to PF01817.17 CM_2, and to PF01842.21 ACT; draft locus tag CAMGR0001_2539.
 
 
 0.990
hisD
Histidinal dehydrogenase / histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 0.986
tyrA
Chorismate mutase / prephenate dehydrogenase; Bifunctional; Pfam match to PF02153.13 PDH; draft locus tag CAMGR0001_1630.
  
 
 0.960
hisH
Imidazole glycerol phosphate synthase HisFH, HisH subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
  
 0.931
aspB
Aspartate aminotransferase, aminotransferase, classes I and II; Pfam match to PF00155.17 Aminotran_1_2; draft locus tag CAMGR0001_0815.
  
 
 0.930
AKT92188.1
Histidinol-phosphate / aromatic aminotransferase; Pfam match to PF00155.17 Aminotran_1_2; draft locus tag CAMGR0001_1510.
  
  
 
0.927
AKT92486.1
D-amino acid aminotransferase; Pfam match to PF01063.15 Aminotran_4; draft locus tag CAMGR0001_1088.
  
 
 0.926
hisJ
Histidinol-phosphate phosphatase; Pfam match to PF02811.15 PHP; draft locus tag CAMGR0001_2874; Belongs to the PHP hydrolase family. HisK subfamily.
 
 
 0.924
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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