| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| glyA | ilvA | CGRAC_1853 | CGRAC_0818 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. | 0.922 |
| glyA | pssA | CGRAC_1853 | CGRAC_1480 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphatidylserine synthase; Pfam match to PF01066.17 CDP-OH_P_transf; draft locus tag CAMGR0001_2003; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| glyA | serB | CGRAC_1853 | CGRAC_0424 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase; Pfam match to PF00702.22 Hydrolase; draft locus tag CAMGR0001_2547. | 0.919 |
| glyA | trpA | CGRAC_1853 | CGRAC_0480 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.927 |
| glyA | trpB | CGRAC_1853 | CGRAC_0479 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.922 |
| glyA | trpDG | CGRAC_1853 | CGRAC_0492 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate phosphoribosyltransferase / anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.501 |
| ilvA | glyA | CGRAC_0818 | CGRAC_1853 | Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.922 |
| ilvA | pssA | CGRAC_0818 | CGRAC_1480 | Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. | Phosphatidylserine synthase; Pfam match to PF01066.17 CDP-OH_P_transf; draft locus tag CAMGR0001_2003; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| ilvA | serB | CGRAC_0818 | CGRAC_0424 | Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. | Phosphoserine phosphatase; Pfam match to PF00702.22 Hydrolase; draft locus tag CAMGR0001_2547. | 0.905 |
| ilvA | trpA | CGRAC_0818 | CGRAC_0480 | Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.916 |
| ilvA | trpB | CGRAC_0818 | CGRAC_0479 | Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.936 |
| ilvA | trpDG | CGRAC_0818 | CGRAC_0492 | Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. | Anthranilate phosphoribosyltransferase / anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.512 |
| lgt | trpA | CGRAC_0796 | CGRAC_0480 | Phosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.853 |
| lgt | trpB | CGRAC_0796 | CGRAC_0479 | Phosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.843 |
| pssA | glyA | CGRAC_1480 | CGRAC_1853 | Phosphatidylserine synthase; Pfam match to PF01066.17 CDP-OH_P_transf; draft locus tag CAMGR0001_2003; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
| pssA | ilvA | CGRAC_1480 | CGRAC_0818 | Phosphatidylserine synthase; Pfam match to PF01066.17 CDP-OH_P_transf; draft locus tag CAMGR0001_2003; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Threonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. | 0.900 |
| pssA | serB | CGRAC_1480 | CGRAC_0424 | Phosphatidylserine synthase; Pfam match to PF01066.17 CDP-OH_P_transf; draft locus tag CAMGR0001_2003; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphoserine phosphatase; Pfam match to PF00702.22 Hydrolase; draft locus tag CAMGR0001_2547. | 0.900 |
| pssA | trpA | CGRAC_1480 | CGRAC_0480 | Phosphatidylserine synthase; Pfam match to PF01066.17 CDP-OH_P_transf; draft locus tag CAMGR0001_2003; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
| pssA | trpB | CGRAC_1480 | CGRAC_0479 | Phosphatidylserine synthase; Pfam match to PF01066.17 CDP-OH_P_transf; draft locus tag CAMGR0001_2003; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| serB | glyA | CGRAC_0424 | CGRAC_1853 | Phosphoserine phosphatase; Pfam match to PF00702.22 Hydrolase; draft locus tag CAMGR0001_2547. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.919 |