STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (401 aa)    
Predicted Functional Partners:
pheT
phenylalanyl-tRNA synthetase, beta subunit; Pfam matches to PF01588.16 tRNA_bind, and to PF03147.10 FDX-ACB, and to PF03484.11 B5, and to PF03483.13 B3_4; draft locus tag CAMGR0001_2845; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.915
metS
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.805
amiA
Pfam matches to PF01520.14 Amidase_3, and to PF11741.4 AMIN; draft locus tag CAMGR0001_1537.
       0.800
npd
Nitronate monooxygenase; Pfam match to PF03060.11 NMO; draft locus tag CAMGR0001_1536.
       0.800
spoT
ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3' pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
  
 0.783
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.778
argS
arginyl-tRNA synthetase; Pfam matches to PF05746.11 DALR_1, and to PF00750.15 tRNA-synt_1d, and to PF03485.12 Arg_tRNA_synt_N; draft locus tag CAMGR0001_1347.
 
  
 0.733
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
    0.726
leuS
leucyl-tRNA synthetase; Pfam matches to PF13603.2 tRNA-synt_1_2, and to PF00133.18 tRNA-synt_1, and to PF09334.7 tRNA-synt_1g; draft locus tag CAMGR0001_1526; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.670
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
 
  
 0.645
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.