STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvAThreonine deaminase; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_1391. (403 aa)    
Predicted Functional Partners:
ilvH
Acetolactate synthase III, valine-sensitive, regulatory (small) subunit; Pfam matches to PF01842.21 ACT, and to PF10369.5 ALS_ss_C; draft locus tag CAMGR0001_1023.
  
 
 0.968
AKT91661.1
Threonine synthase, putative; Pfam match to PF00291.21 PALP; draft locus tag CAMGR0001_0625.
 
 
 0.964
thrC
Threonine synthase; Pfam matches to PF14821.2 Thr_synth_N, and to PF00291.21 PALP; draft locus tag CAMGR0001_1253.
  
 
 0.945
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
  
 
 0.938
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
0.936
ilvI
Acetolactate synthase III, valine-sensitive, catalytic (large) subunit; Pfam matches to PF02776.14 TPP_enzyme_N, and to PF02775.17 TPP_enzyme_C, and to PF00205.18 TPP_enzyme_M; draft locus tag CAMGR0001_1024.
  
 0.928
AKT93337.1
Thiamine pyrophosphate binding domain protein; Pfam matches to PF02776.14 TPP_enzyme_N, and to PF00205.18 TPP_enzyme_M, and to PF02775.17 TPP_enzyme_C; draft locus tag CAMGR0001_0394.
  
 0.928
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.922
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
 0.916
serB
Phosphoserine phosphatase; Pfam match to PF00702.22 Hydrolase; draft locus tag CAMGR0001_2547.
     
 0.905
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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