STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT92329.1Hypothetical protein; Draft locus tag CAMGR0001_1296. (323 aa)    
Predicted Functional Partners:
AKT92886.1
Hypothetical protein; Draft locus tag CAMGR0001_1969.
  
     0.644
AKT92328.1
Hypothetical protein; Draft locus tag CAMGR0001_1297.
       0.558
ctsW
Transformation system, predicted amidophosphoribosyltransferase CtsW; Draft locus tag CAMGR0001_2784.
   
    0.513
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.503
tyrA
Chorismate mutase / prephenate dehydrogenase; Bifunctional; Pfam match to PF02153.13 PDH; draft locus tag CAMGR0001_1630.
  
    0.467
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.458
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.424
polA
DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.415
AKT92655.1
Hypothetical protein; Draft locus tag CAMGR0001_0820.
  
     0.402
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.