STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyfGHydrogenase-4, component G; Pfam matches to PF00346.15 Complex1_49kDa, and to PF00329.15 Complex1_30kDa, and to PF00374.15 NiFeSe_Hases, and to PF00346.15 Complex1_49kDa; draft locus tag CAMGR0001_1282. (578 aa)    
Predicted Functional Partners:
hyfI
Hydrogenase-4, component I; Pfam match to PF01058.18 Oxidored_q6; draft locus tag CAMGR0001_1284.
 
 0.999
hyfH
Hydrogenase-4, component H; Pfam match to PF12838.3 Fer4_7; draft locus tag CAMGR0001_1283.
 
 
 0.999
hyfF
Hydrogenase-4, component F; Pfam matches to PF00361.16 Proton_antipo_M, and to PF00662.16 Proton_antipo_N; draft locus tag CAMGR0001_1281.
 
 
 0.999
hyfC
Hydrogenase-4, component C; Pfam match to PF00146.17 NADHdh; draft locus tag CAMGR0001_1279.
 
 
 0.999
hyfB
Hydrogenase-4, component B; Pfam match to PF00361.16 Proton_antipo_M; draft locus tag CAMGR0001_1278.
 
 
 0.999
hyfE
Hydrogenase-4, membrane component E; Pfam match to PF00420.20 Oxidored_q2; draft locus tag CAMGR0001_1280.
 
  
 0.998
hyfA
Hydrogenase-4, component A; Pfam match to PF13247.2 Fer4_11; draft locus tag CAMGR0001_1277.
 
 
 0.996
nuoI
NADH:quinone oxidoreductase I, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
 0.988
por
Pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Pfam matches to PF01855.15 POR_N, and to PF01558.14 POR, and to PF10371.5 EKR, and to PF12838.3 Fer4_7, and to PF02775.17 TPP_enzyme_C; draft locus tag CAMGR0001_2171.
  
 
 0.987
fdhI
Formate dehydrogenase H, selenocysteine-containing; Pfam matches to PF00384.18 Molybdopterin, and to PF04879.12 Molybdop_Fe4S4; draft locus tags CAMGR0001_1275 and CAMGR0001_1276; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.985
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
Server load: low (16%) [HD]