STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ribFBifunctional riboflavin kinase / FMN adenylyltransferase; Bifunctional; Pfam matches to PF01687.13 Flavokinase, and to PF06574.8 FAD_syn, and to PF01687.13 Flavokinase, and to PF06574.8 FAD_syn; draft locus tag CAMGR0001_1260. (460 aa)    
Predicted Functional Partners:
ribE
6,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase, alpha subunit); Pfam matches to PF00677.13 Lum_binding, and to PF00677.13 Lum_binding; draft locus tag CAMGR0001_1356.
  
 
 0.930
ribH
6,7-dimethyl-8-ribityllumazine synthase (riboflavin synthase, beta subunit); Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.857
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
 
    0.825
AKT92354.1
Lipocalin domain protein; Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.
       0.800
tlyA
16S/23S rRNA (cytidine-2'-O)-methyltransferase; Bifunctional; Pfam match to PF01728.15 FtsJ; draft locus tag CAMGR0001_1258.
       0.800
AKT92356.1
Hypothetical protein; Draft locus tag CAMGR0001_1257.
       0.773
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Pfam match to PF02348.15 CTP_transf_3; draft locus tag CAMGR0001_1254; Belongs to the KdsB family.
       0.766
AKT92358.1
Hypothetical protein; Draft locus tag CAMGR0001_1255.
       0.762
thrC
Threonine synthase; Pfam matches to PF14821.2 Thr_synth_N, and to PF00291.21 PALP; draft locus tag CAMGR0001_1253.
       0.762
ribD
Riboflavin biosynthesis protein RibD; Bifunctional; Pfam match to PF00383.18 dCMP_cyt_deam_1; draft locus tag CAMGR0001_1613.
 
  
 0.745
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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