STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (368 aa)    
Predicted Functional Partners:
lpxB
Lipid A disaccharide synthase; Pfam matches to PF02684.11 LpxB, and to PF02684.11 LpxB; draft locus tag CAMGR0001_2551; Belongs to the LpxB family.
 
  
 0.983
kdtA
3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase); Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
 
 0.981
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Pfam match to PF02348.15 CTP_transf_3; draft locus tag CAMGR0001_1254; Belongs to the KdsB family.
 
   
 0.909
kpsF
D-arabinose 5-phosphate isomerase; Pfam matches to PF01380.18 SIS, and to PF00571.24 CBS; draft locus tag CAMGR0001_0352; Belongs to the SIS family. GutQ/KpsF subfamily.
 
   
 0.882
lpxD
UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
   
 0.836
lpxA
UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.832
kdsA
3-deoxy-D-manno-octulosonate 8-phosphate synthase; Pfam matches to PF00793.16 DAHP_synth_1, and to PF00793.16 DAHP_synth_1; draft locus tag CAMGR0001_0618.
 
   
 0.828
lpxC
UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.825
AKT92363.1
Aminotransferase, DegT/DnrJ/EryC1/StrS family; Pfam match to PF01041.13 DegT_DnrJ_EryC1; draft locus tag CAMGR0001_1250; Belongs to the DegT/DnrJ/EryC1 family.
       0.800
nadE
NAD synthetase, NH3-dependent; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
       0.795
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.