STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (365 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.963
AKT93577.1
Hypothetical membrane protein (UPF0093 domain); Pfam match to PF03653.9 UPF0093; draft locus tag CAMGR0001_0270.
 
  
 0.940
AKT92414.1
Oxidoreductase, Gfo/Idh/MocA family; Pfam match to PF01408.18 GFO_IDH_MocA; draft locus tag CAMGR0001_1180.
     
 0.819
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.593
AKT92416.1
Putative membrane protein; Draft locus tag CAMGR0001_1178.
       0.593
maf
Septum formation protein Maf; Pfam match to PF02545.10 Maf; draft locus tags CAMGR0001_1176 and CAMGR0001_1177.
       0.593
pbpA
Penicillin-binding protein 1A; Bifunctional; Pfam matches to PF00912.18 Transgly, and to PF00905.18 Transpeptidase; draft locus tag CAMGR0001_1175.
       0.593
iscU
Iron-sulfur cluster assembly scaffold protein IscU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
 
   
 0.587
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.543
ccsBA
Cytochrome c biogenesis protein; Pfam matches to PF01578.16 Cytochrom_C_asm, and to PF05140.10 ResB, and to PF05140.10 ResB; draft locus tag CAMGR0001_1840.
  
  
 0.513
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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