Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yqeVMiaB-like tRNA modifying enzyme; Pfam matches to PF00919.16 UPF0004, and to PF04055.17 Radical_SAM; draft locus tag CAMGR0001_1124. (410 aa)    
Predicted Functional Partners:
ftsH1
Integral membrane ATP-dependent zinc metallopeptidase; Pfam matches to PF00004.25 AAA, and to PF01434.14 Peptidase_M41; draft locus tags CAMGR0001_1122 and CAMGR0001_1123; Belongs to the AAA ATPase family.
     
 0.817
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
       0.814
AKT92456.1
Mechanosensitive ion channel family protein; Pfam match to PF00924.14 MS_channel; draft locus tag CAMGR0001_1125.
       0.814
mogA
Molybdopterin adenylyltransferase; Pfam match to PF00994.20 MoCF_biosynth; draft locus tag CAMGR0001_1121.
       0.735
AKT92454.1
Putative protein (putative TrkA domain); Pfam match to PF02080.17 TrkA_C; draft locus tag CAMGR0001_1127.
       0.701
mrp
ATP/GTP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
   
 0.652
rlmN
23S rRNA m2A2503 methyltransferase / tRNA m2A37 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
  
 0.520
AKT92460.1
Hypothetical protein; Draft locus tag CAMGR0001_1120.
       0.511
AKT92461.1
Hypothetical protein; Draft locus tag CAMGR0001_1119.
       0.511
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...]
  
  
 0.435
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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