STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (518 aa)    
Predicted Functional Partners:
hemL
Glutamate-1-semialdehyde aminotransferase; Pfam match to PF00202.17 Aminotran_3; draft locus tag CAMGR0001_0751.
 
 0.987
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.948
gltX2
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.909
hemB
Porphobilinogen synthase; Pfam match to PF00490.17 ALAD; draft locus tag CAMGR0001_1808; Belongs to the ALAD family.
 
  
 0.841
ispB
Octaprenyl-diphosphate synthase; Pfam match to PF00348.13 polyprenyl_synt; draft locus tag CAMGR0001_1009; Belongs to the FPP/GGPP synthase family.
  
  
 0.803
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.800
AKT92536.1
Putative protein (DUF2018 domain); Pfam match to PF09442.6 DUF2018; draft locus tag CAMGR0001_1008.
       0.800
ccsBA
Cytochrome c biogenesis protein; Pfam matches to PF01578.16 Cytochrom_C_asm, and to PF05140.10 ResB, and to PF05140.10 ResB; draft locus tag CAMGR0001_1840.
  
  
 0.545
AKT93425.1
Cytochrome c biogenesis protein; Pfam matches to PF01578.16 Cytochrom_C_asm, and to PF05140.10 ResB, and to PF05140.10 ResB; draft locus tag CAMGR0001_2227.
  
  
 0.545
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.488
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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