STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqnCDehypoxanthinylfutalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). (349 aa)    
Predicted Functional Partners:
mqnD
1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
  
 0.979
pfs
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
     
 0.902
ubiA
4-hydroxybenzoate octaprenyltransferase; Pfam match to PF01040.14 UbiA; draft locus tag CAMGR0001_2671; Belongs to the UbiA prenyltransferase family.
 
   
 0.803
AKT92648.1
Paraslipin family protein, SPFH superfamily; Pfam match to PF01145.21 Band_7; draft locus tag CAMGR0001_0830.
  
    0.780
AKT92649.1
Putative slipin-associated protein (NfeD domain); Pfam match to PF01957.14 NfeD; draft locus tag CAMGR0001_0829.
       0.776
AKT92650.1
Nucleotidyl transferase domain protein; Pfam match to PF01909.19 NTP_transf_2; draft locus tag CAMGR0001_0828.
       0.773
AKT92651.1
Hypothetical protein; Draft locus tag CAMGR0001_0827.
       0.773
AKT93538.1
Putative PAS sensor-containing diguanylate phosphodiesterase; Pfam matches to PF00563.16 EAL, and to PF00989.20 PAS; draft locus tag CAMGR0001_0214.
 
 
 0.698
thiG
ThiGH complex, thiazole synthase subunit ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.669
thiC
HMP-P synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
  
  
 0.600
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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