STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
murDPfam match to PF08245.8 Mur_ligase_M; draft locus tag CAMGR0001_2078; Belongs to the MurCDEF family. (491 aa)    
Predicted Functional Partners:
mraY
phospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
 0.997
murC
UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 
 0.997
murE
UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
 
 0.990
murG
N-acetylglucosaminyl transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.974
murF
D-alanyl-D-alanine-adding enzyme; Pfam match to PF08245.8 Mur_ligase_M; draft locus tag CAMGR0001_0853.
 
  
 0.945
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
    
 0.932
ddlA
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
  
 0.921
purQ
Phosphoribosylformylglycinamidine synthase PurLQS, glutaminase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and [...]
     
  0.900
ftsW
Cell division protein, FtsW/RodA/SpoVE family; Pfam match to PF01098.15 FTSW_RODA_SPOVE; draft locus tag CAMGR0001_0794; Belongs to the SEDS family.
 
  
 0.876
ftsI
Cell division protein FtsI / penicillin-binding protein; Pfam matches to PF00905.18 Transpeptidase, and to PF03717.11 PBP_dimer; draft locus tag CAMGR0001_1185.
 
  
 0.862
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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