STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gppAGuanosine-5'-triphosphate, 3'-diphosphate pyrophosphatase; Pfam match to PF02541.12 Ppx-GppA; draft locus tag CAMGR0001_0519. (480 aa)    
Predicted Functional Partners:
spoT
ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3' pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.930
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
  
 0.922
AKT93246.1
Ferredoxin; Draft locus tag CAMGR0001_0518.
       0.800
cosR
Two-component system response regulator; Pfam matches to PF00072.20 Response_reg, and to PF00486.24 Trans_reg_C; draft locus tag CAMGR0001_0516.
     
 0.671
cosS
Two-component system sensor histidine kinase; Pfam matches to PF02518.22 HATPase_c, and to PF00512.21 HisKA; draft locus tag CAMGR0001_0517.
       0.665
folB
Dihydroneopterin aldolase; Pfam match to PF02152.14 FolB; draft locus tag CAMGR0001_0515.
       0.524
plsY
Acyl phosphate:glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
       0.524
AKT93251.1
Putative protein (AAA domain); Pfam match to PF12846.3 AAA_10; draft locus tag CAMGR0001_0513.
       0.496
ppk2
Polyphosphate kinase 2; Pfam match to PF03976.10 PPK2; draft locus tag CAMGR0001_2368.
 
  
 0.458
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.441
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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