STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKT93359.1Metallo-dependent hydrolase, subgroup D; Pfam match to PF01979.16 Amidohydro_1; draft locus tag CAMGR0001_2492. (405 aa)    
Predicted Functional Partners:
mqnE
Menaquinone biosynthesis protein, SCO4494 family; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
 
  
  0.938
pfs
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
     
 0.901
sppA
Signal peptide peptidase protease IV; Pfam match to PF01343.14 Peptidase_S49; draft locus tag CAMGR0001_2493.
       0.800
pepQ
X-Pro dipeptidase; Pfam match to PF00557.20 Peptidase_M24; draft locus tag CAMGR0001_2490.
 
 
 0.652
aroD
3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
       0.569
folK
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; Pfam match to PF01288.16 HPPK; draft locus tag CAMGR0001_2489.
       0.550
AKT93363.1
Hypothetical protein; Pfam match to PF01656.19 CbiA; draft locus tag CAMGR0001_2488.
       0.550
mqnD
1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
  
     0.475
pheA
Chorismate mutase / prephenate dehydratase; Bifunctional; Pfam matches to PF00800.14 PDT, and to PF01817.17 CM_2, and to PF01842.21 ACT; draft locus tag CAMGR0001_2539.
   
 
 0.448
AKT93364.1
Putative lysine decarboxylase family protein; Pfam match to PF03641.10 Lysine_decarbox; draft locus tag CAMGR0001_2487; Belongs to the LOG family.
       0.420
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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