STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (203 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.990
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.989
carB
Carbamoylphosphate synthase, large subunit; Pfam matches to PF02786.13 CPSase_L_D2, and to PF02786.13 CPSase_L_D2, and to PF02787.15 CPSase_L_D3, and to PF02142.18 MGS; draft locus tag CAMGR0001_2714; Belongs to the CarB family.
  
 
 0.906
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Pfam matches to PF02729.17 OTCace_N, and to PF00185.20 OTCace; draft locus tag CAMGR0001_1584; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.898
carA
Carbamoylphosphate synthase, small subunit; Pfam matches to PF00117.24 GATase, and to PF00988.18 CPSase_sm_chain; draft locus tag CAMGR0001_2631; Belongs to the CarA family.
  
  
 0.882
AKT92787.1
Pfam match to PF00860.16 Xan_ur_permease; draft locus tag CAMGR0001_2395.
  
  
 0.861
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.850
frr
Ribosome releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
    0.818
pyrC2
Dihydroorotase, multifunctional complex type; Pfam match to PF01979.16 Amidohydro_1; draft locus tags CAMGR0001_1582 and CAMGR0001_1583.
  
  
 0.793
iadA
Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation.
  
  
 0.793
Your Current Organism:
Campylobacter gracilis
NCBI taxonomy Id: 824
Other names: ATCC 33236, Bacteroides gracilis, C. gracilis, CCUG 27720, DSM 19528, JCM 8538, NCTC 12738
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