| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT91550.1 | def | CGRAC_0078 | CGRAC_0079 | Mg chelatase-related protein; Pfam matches to PF01078.17 Mg_chelatase, and to PF13541.2 ChlI, and to PF13335.2 Mg_chelatase_C; draft locus tag CAMGR0001_0109. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.837 |
| AKT91550.1 | ruvC | CGRAC_0078 | CGRAC_2189 | Mg chelatase-related protein; Pfam matches to PF01078.17 Mg_chelatase, and to PF13541.2 ChlI, and to PF13335.2 Mg_chelatase_C; draft locus tag CAMGR0001_0109. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.678 |
| AKT93580.1 | pncA | CGRAC_2188 | CGRAC_2187 | Hydrolase, carbon-nitrogen family; Pfam match to PF00795.18 CN_hydrolase; draft locus tag CAMGR0001_0273. | Pyrazinamidase / nicotinamidase; Bifunctional; Pfam match to PF00857.16 Isochorismatase; draft locus tag CAMGR0001_0272. | 0.800 |
| AKT93580.1 | ruvC | CGRAC_2188 | CGRAC_2189 | Hydrolase, carbon-nitrogen family; Pfam match to PF00795.18 CN_hydrolase; draft locus tag CAMGR0001_0273. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.773 |
| def | AKT91550.1 | CGRAC_0079 | CGRAC_0078 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Mg chelatase-related protein; Pfam matches to PF01078.17 Mg_chelatase, and to PF13541.2 ChlI, and to PF13335.2 Mg_chelatase_C; draft locus tag CAMGR0001_0109. | 0.837 |
| def | ruvC | CGRAC_0079 | CGRAC_2189 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.407 |
| dnaE | polA | CGRAC_1865 | CGRAC_1825 | DNA polymerase III, alpha subunit; Pfam matches to PF07733.8 DNA_pol3_alpha, and to PF02811.15 PHP, and to PF14579.2 HHH_6; draft locus tag CAMGR0001_0475. | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.662 |
| dnaE | ruvC | CGRAC_1865 | CGRAC_2189 | DNA polymerase III, alpha subunit; Pfam matches to PF07733.8 DNA_pol3_alpha, and to PF02811.15 PHP, and to PF14579.2 HHH_6; draft locus tag CAMGR0001_0475. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.468 |
| dnaE | topA | CGRAC_1865 | CGRAC_0107 | DNA polymerase III, alpha subunit; Pfam matches to PF07733.8 DNA_pol3_alpha, and to PF02811.15 PHP, and to PF14579.2 HHH_6; draft locus tag CAMGR0001_0475. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.550 |
| pncA | AKT93580.1 | CGRAC_2187 | CGRAC_2188 | Pyrazinamidase / nicotinamidase; Bifunctional; Pfam match to PF00857.16 Isochorismatase; draft locus tag CAMGR0001_0272. | Hydrolase, carbon-nitrogen family; Pfam match to PF00795.18 CN_hydrolase; draft locus tag CAMGR0001_0273. | 0.800 |
| pncA | ruvC | CGRAC_2187 | CGRAC_2189 | Pyrazinamidase / nicotinamidase; Bifunctional; Pfam match to PF00857.16 Isochorismatase; draft locus tag CAMGR0001_0272. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.774 |
| polA | dnaE | CGRAC_1825 | CGRAC_1865 | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA polymerase III, alpha subunit; Pfam matches to PF07733.8 DNA_pol3_alpha, and to PF02811.15 PHP, and to PF14579.2 HHH_6; draft locus tag CAMGR0001_0475. | 0.662 |
| polA | recJ | CGRAC_1825 | CGRAC_2112 | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Single-stranded DNA-specific exonuclease; Pfam matches to PF02272.15 DHHA1, and to PF01368.16 DHH; draft locus tag CAMGR0001_0175. | 0.640 |
| polA | ruvA | CGRAC_1825 | CGRAC_1191 | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RuvABC resolvasome, subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.627 |
| polA | ruvB | CGRAC_1825 | CGRAC_1371 | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RuvABC resolvasome, subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.691 |
| polA | ruvC | CGRAC_1825 | CGRAC_2189 | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.630 |
| polA | topA | CGRAC_1825 | CGRAC_0107 | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.897 |
| recJ | polA | CGRAC_2112 | CGRAC_1825 | Single-stranded DNA-specific exonuclease; Pfam matches to PF02272.15 DHHA1, and to PF01368.16 DHH; draft locus tag CAMGR0001_0175. | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.640 |
| recJ | ruvC | CGRAC_2112 | CGRAC_2189 | Single-stranded DNA-specific exonuclease; Pfam matches to PF02272.15 DHHA1, and to PF01368.16 DHH; draft locus tag CAMGR0001_0175. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.409 |
| recJ | topA | CGRAC_2112 | CGRAC_0107 | Single-stranded DNA-specific exonuclease; Pfam matches to PF02272.15 DHHA1, and to PF01368.16 DHH; draft locus tag CAMGR0001_0175. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.584 |