STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
thiGThiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (294 aa)    
Predicted Functional Partners:
AFY71343.1
PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS; InterPro IPR010035:IPR003749; KEGG: ava:Ava_5046 hypothetical protein; PFAM: ThiamineS; SPTR: ThiS, thiamine-biosynthesis; TIGRFAM: ThiS, thiamine-biosynthesis.
 
 
 0.999
AFY71398.1
Glycine oxidase; PFAM: FAD dependent oxidoreductase; TIGRFAM: glycine oxidase ThiO; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR012727:IPR006076; KEGG: ter:Tery_0284 glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; PRIAM: Glycine oxidase; SPTR: Thiazole biosynthesis protein ThiG, putative; TIGRFAM: Glycine oxidase ThiO.
 
 0.996
AFY69944.1
UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; Rhodanese-like domain; ThiF family; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901:IPR001763; KEGG: tel:tlr2403 hypothetical protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; Rhodanese-like; SMART: Rhodanese-like; SPTR: Molybdopterin biosynthesis protein MoeB.
  
 0.992
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
 0.974
AFY69993.1
PFAM: FAD dependent oxidoreductase; COGs: COG0665 Glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: npu:Npun_F5243 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase.
 
 0.968
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.929
AFY68796.1
PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004399; KEGG: cyb:CYB_2833 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2.
 
  
 0.858
AFY71225.1
Thiamine S protein; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal; InterPro IPR003749; KEGG: cyc:PCC7424_1889 MoaD family protein; PFAM: ThiamineS; SPTR: Putative uncharacterized protein.
   
 
 0.643
AFY71701.1
Molybdopterin synthase subunit MoaD; PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal; InterPro IPR003749; KEGG: amr:AM1_0919 thiamineS protein, putative; PFAM: ThiamineS; SPTR: ThiamineS protein, putative.
   
 
 0.643
panC/cmk
Cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.
     
 0.474
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
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