STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
AFY68933.1Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: ana:all4963 adenylate cyclase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Adenyly [...] (1163 aa)    
Predicted Functional Partners:
AFY68790.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR001789:IPR003661:IPR003594; KEGG: cyj:Cyan7822_3901 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction response regulator, re [...]
 
 
0.999
AFY68831.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013767; KEGG: ava:Ava_1564 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; SMART: ATPase-l [...]
 
 
0.999
AFY68834.1
Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR001789:IPR000014:IPR001610:IPR003018:IPR 003661:IPR003594:IPR013767; KEGG: cyc:PCC7424_2021 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; PAS fold; GAF; Signal transduction histidine kinase, subgro [...]
 
 
0.999
AFY68932.1
Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013655:IPR003018:IPR003594:IPR000014:IPR 001610:IPR003661; KEGG: npu:Npun_F1203 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold-3; GAF; SMART: ATPase-like, ATP-binding domain; PAC motif; PAS; GAF; Signal transduction histidine kina [...]
 
 
0.999
AFY68974.1
PAS/PAC sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR013767:IPR003594:IPR000014:IPR001610; KEGG: npu:Npun_AR133 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; PAS fold; SMART: ATPase-like, ATP-binding domain; PAS; PAC motif; SPTR: Putative two component sensor histidine kinase; TIGRFAM: PAS.
 
 
 
0.999
AFY69005.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR003661:IPR003594; KEGG: ava:Ava_0649 response regulator receiver signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction resp [...]
 
 
0.999
AFY69063.1
Multi-sensor hybrid histidine kinase; PFAM: Cache domain; HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004010:IPR003660:IPR013767:IPR013656:IPR 013655:IPR003018:IPR003661:IPR003594:IPR001789:IPR000014:I PR001610; KEGG: npu:Npun_R5897 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor do [...]
 
 
0.999
AFY69105.1
Multi-sensor hybrid histidine kinase; PFAM: Cache domain; HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR001789:IPR 000014; KEGG: npu:Npun_R4744 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase [...]
 
 
0.999
AFY69115.1
Multi-sensor signal transduction histidine kinase; PFAM: Cache domain; HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR013655:IPR013767:IPR003661:IPR 003594:IPR000014:IPR001610; KEGG: npu:Npun_R2408 multi-sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; PAS fold-3; PAS fold; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMA [...]
 
 
0.999
AFY69132.1
Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR013656:IPR013767:IPR003018:IPR003594:IPR 000014:IPR001610; KEGG: npu:Npun_R6149 multi-sensor signal transduction histidine kinase; PFAM: GAF; PAS fold-4; PAS fold; ATPase-like, ATP-binding domain; SMART: GAF; PAS; PAC motif; ATPase-like, ATP-binding domain; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS.
 
 
0.999
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
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