STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY69374.1SMC domain protein; PFAM: RecF/RecN/SMC N terminal domain; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395:IPR003593; KEGG: gau:GAU_0775 exonuclease; PFAM: RecF/RecN/SMC; SMART: ATPase, AAA+ type, core; SPTR: Exonuclease. (809 aa)    
Predicted Functional Partners:
AFY69954.1
Metallophosphoesterase; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: gau:GAU_0774 exonuclease; PFAM: Metallo-dependent phosphatase; SPTR: Exonuclease.
 
 0.972
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
 0.949
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.946
AFY71155.1
Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: TIGR04168 family protein; InterPro IPR004843; KEGG: cyh:Cyan8802_4496 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Ser/Thr protein phosphatase family protein.
  
 0.887
AFY70621.1
ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; COGs: COG0514 Superfamily II DNA helicase; InterPro IPR014001:IPR001650:IPR011545:IPR004589; KEGG: cyh:Cyan8802_4440 ATP-dependent DNA helicase, RecQ family; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: DNA helicase, ATP-dependent, RecQ type.
  
 0.784
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.777
AFY70420.1
KEGG: rxy:Rxyl_0452 hypothetical protein; SPTR: Conserved hypothetical cytosolic protein.
 
     0.605
recA
Protein recA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.591
smc
Condensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.582
AFY69931.1
PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070; KEGG: syp:SYNPCC7002_A1242 YrdC domain-containing protein; PFAM: Sua5/YciO/YrdC, N-terminal; SPTR: YrdC domain protein; Belongs to the SUA5 family.
  
   0.445
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
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