STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Coexpression
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[Homology]
Score
AFY69998.1Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR013767:IPR013655:IPR 003018:IPR003661:IPR003594:IPR001610; KEGG: rci:RCIX2113 putative signal transduction protein; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response [...] (1742 aa)    
Predicted Functional Partners:
AFY68831.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013767; KEGG: ava:Ava_1564 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; SMART: ATPase-l [...]
 
 
0.999
AFY68933.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: ana:all4963 adenylate cyclase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Adenyly [...]
  
 
0.999
AFY69063.1
Multi-sensor hybrid histidine kinase; PFAM: Cache domain; HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004010:IPR003660:IPR013767:IPR013656:IPR 013655:IPR003018:IPR003661:IPR003594:IPR001789:IPR000014:I PR001610; KEGG: npu:Npun_R5897 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor do [...]
 
 
0.999
AFY69105.1
Multi-sensor hybrid histidine kinase; PFAM: Cache domain; HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR001789:IPR 000014; KEGG: npu:Npun_R4744 PAS/PAC sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase [...]
 
 
0.999
AFY69210.1
PFAM: Response regulator receiver domain; Hpt domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR008207; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction response regulator, receiver domain; SMART: Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction response regulator, receiver domain; SPTR: Sensory box histidine kinase/response regulator.
 
 
 0.999
AFY69545.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR003594:IPR002545:IPR001789; KEGG: amr:AM1_0913 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; CheW-like protein; SMART: Signal transduction response regulator, receiver [...]
 
 
 0.999
AFY69679.1
PFAM: HAMP domain; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004010:IPR003660:IPR003661:IPR003594:IPR 001789; KEGG: scl:sce5571 two-component hybrid sensor and regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Cache; HAMP linker domain; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; Sign [...]
 
 
0.999
AFY69873.1
Diguanylate cyclase; PFAM: GGDEF domain; GAF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018:IPR001610; KEGG: npu:Npun_F1553 diguanylate cyclase with PAS/PAC and GAF sensors; PFAM: Diguanylate cyclase, predicted; GAF; SMART: Diguanylate cyclase, predicted; GAF; PAC motif; SPTR: PleD-like protein; TIGRFAM: Diguanylate cyclase, predicted.
  
 
 0.999
AFY70201.1
PFAM: Response regulator receiver domain; GGDEF domain; Transcriptional regulatory protein, C terminal; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR000160:IPR001789:IPR001867; KEGG: cyc:PCC7424_2752 multi-component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, C-terminal; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SMART: Signal transduction response regulator, C-termi [...]
 
 
 0.999
AFY70226.1
Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR003018:IPR001610:IPR 003661:IPR003594:IPR013767:IPR013656:IPR013655; KEGG: cyj:Cyan7822_4408 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; [...]
 
 
0.999
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
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