node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFY68463.1 | AFY70084.1 | Pse7367_0146 | Pse7367_1807 | Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: ter:Tery_2905 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-binding protein. | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | 0.748 |
AFY68463.1 | AFY70305.1 | Pse7367_0146 | Pse7367_2034 | Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: ter:Tery_2905 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-binding protein. | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | 0.639 |
AFY68463.1 | AFY71416.1 | Pse7367_0146 | Pse7367_3168 | Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: ter:Tery_2905 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-binding protein. | PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR013767:IPR003661:IPR 003594:IPR001610:IPR003018; KEGG: syf:Synpcc7942_1816 periplasmic sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; SMART: ATPase-like, AT [...] | 0.402 |
AFY70084.1 | AFY68463.1 | Pse7367_1807 | Pse7367_0146 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: ter:Tery_2905 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-binding protein. | 0.748 |
AFY70084.1 | AFY70305.1 | Pse7367_1807 | Pse7367_2034 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | 0.771 |
AFY70084.1 | AFY70665.1 | Pse7367_1807 | Pse7367_2404 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: amr:AM1_4373 mechanosensitive ion channel, putative; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Putative uncharacterized protein. | 0.773 |
AFY70084.1 | AFY71416.1 | Pse7367_1807 | Pse7367_3168 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR013767:IPR003661:IPR 003594:IPR001610:IPR003018; KEGG: syf:Synpcc7942_1816 periplasmic sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; SMART: ATPase-like, AT [...] | 0.749 |
AFY70084.1 | AFY71768.1 | Pse7367_1807 | Pse7367_3533 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
AFY70084.1 | AFY71801.1 | Pse7367_1807 | Pse7367_3566 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602; KEGG: syd:Syncc9605_0732 GTP cyclohydrolase; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase I. | 0.803 |
AFY70084.1 | cpdA | Pse7367_1807 | Pse7367_2450 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.906 |
AFY70084.1 | moaA | Pse7367_1807 | Pse7367_3376 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.812 |
AFY70084.1 | ndk | Pse7367_1807 | Pse7367_2174 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.907 |
AFY70084.1 | ribBA | Pse7367_1807 | Pse7367_1108 | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.832 |
AFY70305.1 | AFY68463.1 | Pse7367_2034 | Pse7367_0146 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: ter:Tery_2905 cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide-binding protein. | 0.639 |
AFY70305.1 | AFY70084.1 | Pse7367_2034 | Pse7367_1807 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain; FHA domain; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000253:IPR003018:IPR001054; KEGG: amr:AM1_3189 adenylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; GAF; Forkhead-associated (FHA) domain; SMART: GAF; Forkhead-associated (FHA) domain; Adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate and Guanylate cyclase catalytic domain protein. | 0.771 |
AFY70305.1 | AFY70665.1 | Pse7367_2034 | Pse7367_2404 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | Putative transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: amr:AM1_4373 mechanosensitive ion channel, putative; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Putative uncharacterized protein. | 0.680 |
AFY70305.1 | AFY71768.1 | Pse7367_2034 | Pse7367_3533 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
AFY70305.1 | AFY71801.1 | Pse7367_2034 | Pse7367_3566 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602; KEGG: syd:Syncc9605_0732 GTP cyclohydrolase; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase I. | 0.800 |
AFY70305.1 | cpdA | Pse7367_2034 | Pse7367_2450 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | Metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.900 |
AFY70305.1 | moaA | Pse7367_2034 | Pse7367_3376 | Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Adenylate and Guanylate cyclase catalytic domain; InterPro IPR019734:IPR001440; KEGG: hoh:Hoch_4571 adenylate/guanylate cyclase with GAF sensor and FHA domain protein; PFAM: Tetratricopeptide TPR-1; SPTR: Adenylate/guanylate cyclase with GAF sensor and FHA domain protein. | Cyclic pyranopterin monophosphate synthase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.804 |