STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AFY70387.1Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa)    
Predicted Functional Partners:
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 0.999
AFY71400.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.999
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 0.996
fabH
3-oxoacyl-(acyl-carrier-protein) synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
 
 
 0.982
AFY68906.1
PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR013747; KEGG: cpi:Cpin_2173 3-oxoacyl-(acyl carrier protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C-terminal; SPTR: 3-oxoacyl-(Acyl carrier protein) synthase.
  
 
 0.974
AFY71284.1
PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410:IPR020801; KEGG: cyt:cce_1583 malonyl coenzyme A-acyl carrier protein transacylase; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SMART: Polyketide synthase, acyl transferase domain; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase.
 
 
 0.970
AFY68775.1
Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: naz:Aazo_1439 hypothetical protein; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; E3 binding; Biotin/lipoyl attachment; SPTR: Catalytic [...]
  
 
 0.927
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
    
 0.910
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
     
 0.900
AFY70487.1
PFAM: HMGL-like; TIGRFAM: homocitrate synthase; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR011872; KEGG: cyc:PCC7424_0947 homocitrate synthase; PFAM: Pyruvate carboxyltransferase; PRIAM: Homocitrate synthase; SPTR: Homocitrate synthase; TIGRFAM: Homocitrate synthase, fungi/archaea; Belongs to the alpha-IPM synthase/homocitrate synthase family.
     
 0.900
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
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