STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (215 aa)    
Predicted Functional Partners:
AFY71200.1
KEGG: tan:TA20975 deoxyuridine 5'-triphosphate nucleotidohydrolase; SPTR: Deoxyuridine 5'-triphosphate nucleotidohydrolase superfamily; Belongs to the dUTPase family.
 
 
 0.957
AFY70197.1
PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125; KEGG: naz:Aazo_5014 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: Cytidine and deoxycytidylate deaminase zinc-binding region domain protein.
    
 0.936
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.932
thyX
Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.930
AFY68664.1
TIGRFAM: intein N-terminal splicing region; ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; COGs: COG1372 Intein/homing endonuclease; InterPro IPR003587:IPR013345:IPR006141; KEGG: syf:Synpcc7942_1609 protein splicing (intein) site; SMART: Hedgehog/intein hint, N-terminal; SPTR: Protein splicing (Intein) site; TIGRFAM: Ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; Intein splice site.
   
 
  0.906
AFY68845.1
5'-nucleotidase, exopolyphosphatase, 3'-nucleotidase; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE; COGs: COG0496 acid phosphatase; InterPro IPR002828; KEGG: npu:Npun_R1763 stationary phase survival protein SurE; PFAM: Survival protein SurE-like phosphatase/nucleotidase; SPTR: Stationary-phase survival protein SurE; TIGRFAM: Survival protein SurE-like phosphatase/nucleotidase.
    
  0.906
surE
5'-nucleotidase, exopolyphosphatase, 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.906
recR
DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
    
 0.874
AFY70405.1
PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570:IPR000462; KEGG: syp:SYNPCC7002_A0877 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.836
mltG
Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
 
  
 0.820
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
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