STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY70824.1Exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: cyh:Cyan8802_1017 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: Exodeoxyribonuclease III; SPTR: Exodeoxyribonuclease III; TIGRFAM: AP endonuclease, family 1; Exodeoxyribonuclease III xth. (276 aa)    
Predicted Functional Partners:
nth
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
 
 0.992
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.934
AFY69755.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.898
AFY68854.1
KEGG: amr:AM1_2350 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 
 0.749
AFY69083.1
PFAM: Methylpurine-DNA glycosylase (MPG); TIGRFAM: DNA-3-methyladenine glycosylase (3mg); COGs: COG2094 3-methyladenine DNA glycosylase; HAMAP: Methylpurine-DNA glycosylase (MPG); InterPro IPR003180; KEGG: cya:CYA_0301 DNA-3-methyladenine glycosylase; PFAM: Methylpurine-DNA glycosylase (MPG); PRIAM: DNA-3-methyladenine glycosylase II; SPTR: Putative 3-methyladenine DNA glycosylase; TIGRFAM: Methylpurine-DNA glycosylase (MPG); Belongs to the DNA glycosylase MPG family.
    
 0.720
AFY69978.1
Ribosomal large subunit pseudouridine synthase B; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR000748:IPR002942:IPR006145; KEGG: cyt:cce_4507 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; Belongs to the pseudouridine synthase RsuA family.
  
    0.706
AFY71743.1
Pseudouridine synthase Rsu; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR000748:IPR006145; KEGG: npu:Npun_F0754 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; Belongs to the pseudouridine synthase RsuA family.
  
    0.706
tadA
tRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
   
 
 0.604
AFY71154.1
Guanine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125; KEGG: fsu:Fisuc_2567 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase, zinc-binding; PRIAM: Guanine deaminase; SPTR: CMP/dCMP deaminase zinc-binding protein.
   
 
 0.604
AFY68933.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: ana:all4963 adenylate cyclase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Adenyly [...]
  
  
 0.505
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
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