STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY70913.1PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterProIPR001789:IPR013767:IPR001054:IPR000014:IPR 001610; KEGG: ter:Tery_2417 adenylate/guanylate cyclase; PFAM: Adenylyl cyclase class-3/4/guanylyl cyclase; Signal transduction response regulator, receiver domain; PAS fold; SMART: Adenylyl cyclase class-3/4/guanylyl cyclase; Signal transduction response regulator, receiver domain; PAS; PAC motif; SPTR: Adenylate/guanylate cyclase; [...] (933 aa)    
Predicted Functional Partners:
AFY68831.1
PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013767; KEGG: ava:Ava_1564 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold; Signal transduction response regulator, receiver domain; SMART: ATPase-l [...]
 
 
 0.999
AFY68933.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: ana:all4963 adenylate cyclase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Adenyly [...]
 
 
0.999
AFY69210.1
PFAM: Response regulator receiver domain; Hpt domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR008207; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction response regulator, receiver domain; SMART: Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction response regulator, receiver domain; SPTR: Sensory box histidine kinase/response regulator.
  
 
 0.999
AFY69760.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR001789:IPR003594; KEGG: npu:Npun_F1212 response regulator receiver sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver domain; ATPase-like, ATP-binding domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Response regulator receiver sensor signal transduction histidine kinase.
 
 0.999
AFY70454.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013767:IPR013656:IPR013655; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; PAS fold; PAS fold-4; Signal transduction response [...]
  
 
0.999
AFY70511.1
PFAM: Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004010:IPR013655; KEGG: ava:Ava_3975 cache sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; PAS fold-3; Cache; Signal transduction response regulator, receiver domain; SMART: Signa [...]
  
 
 0.999
AFY71416.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR013767:IPR003661:IPR 003594:IPR001610:IPR003018; KEGG: syf:Synpcc7942_1816 periplasmic sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; SMART: ATPase-like, AT [...]
 
 
0.999
AFY69063.1
Multi-sensor hybrid histidine kinase; PFAM: Cache domain; HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004010:IPR003660:IPR013767:IPR013656:IPR 013655:IPR003018:IPR003661:IPR003594:IPR001789:IPR000014:I PR001610; KEGG: npu:Npun_R5897 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor do [...]
  
 
0.992
AFY71329.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594:IPR001789; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, s [...]
  
 
 0.991
AFY69998.1
Multi-sensor signal transduction histidine kinase; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR013767:IPR013655:IPR 003018:IPR003661:IPR003594:IPR001610; KEGG: rci:RCIX2113 putative signal transduction protein; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response [...]
  
 
 0.989
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.