STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFY70916.1PFAM: Bacterial regulatory proteins, luxR family; FHA domain; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000253:IPR000792; KEGG: tel:tll2410 adenylate cyclase; PFAM: Transcription regulator LuxR, C-terminal; Forkhead-associated (FHA) domain; SMART: Transcription regulator LuxR, C-terminal; Forkhead-associated (FHA) domain; SPTR: Adenylate cyclase. (242 aa)    
Predicted Functional Partners:
AFY69210.1
PFAM: Response regulator receiver domain; Hpt domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR008207; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction response regulator, receiver domain; SMART: Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction response regulator, receiver domain; SPTR: Sensory box histidine kinase/response regulator.
  
 
 0.861
AFY68933.1
Adenylate/guanylate cyclase with GAF sensor(s); PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003018:IPR003661:IPR003594:IPR 001054; KEGG: ana:all4963 adenylate cyclase; PFAM: ATPase-like, ATP-binding domain; Signal transduction response regulator, receiver domain; GAF; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Adenyly [...]
  
 
 0.805
AFY71416.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR013767:IPR003661:IPR 003594:IPR001610:IPR003018; KEGG: syf:Synpcc7942_1816 periplasmic sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; Signal transduction response regulator, receiver domain; PAS fold; SMART: ATPase-like, AT [...]
  
 
 0.789
AFY70454.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003018:IPR003661:IPR 003594:IPR001789:IPR013767:IPR013656:IPR013655; KEGG: npu:Npun_F2363 multi-sensor hybrid histidine kinase; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; PAS fold-3; PAS fold; PAS fold-4; Signal transduction response [...]
  
 
 0.759
AFY70781.1
Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cyn:Cyan7425_4561 two component transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver domain; SMART: Transcription regulator LuxR, C-terminal; Signal transduction response regulator, receiver domain; SPTR: Two component transcript [...]
  
    0.756
AFY71038.1
Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cyn:Cyan7425_1053 two component transcriptional regulator, LuxR family; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Two component transcript [...]
  
    0.754
AFY71329.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003661:IPR003594:IPR001789; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; GAF; Signal transduction response regulator, receiver domain; SMART: ATPase-like, ATP-binding domain; GAF; Signal transduction histidine kinase, s [...]
  
 
 0.731
AFY70587.1
Two component transcriptional regulator, LuxR family; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ana:alr0913 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: Two-component response regulator.
  
    0.714
AFY69576.1
PFAM: Protein kinase domain; GGDEF domain; GAF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3899 ATPase; InterProIPR000160:IPR017442:IPR003018:IPR020635:IPR 002290; KEGG: npu:Npun_F3565 multi-sensor signal transduction multi-kinase; PFAM: Diguanylate cyclase, predicted; Serine/threonine-protein kinase-like domain; GAF; SMART: Diguanylate cyclase, predicted; Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; GAF; SPTR: Sensor protein; TIGRFAM: Diguanylate cyclase, predicted.
  
 
 0.707
AFY68477.1
Putative PAS/PAC sensor protein; PFAM: Protein kinase domain; GAF domain; Stage II sporulation protein E (SpoIIE); PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3899 ATPase; InterProIPR002290:IPR020635:IPR019734:IPR003018:IPR 000014:IPR001932:IPR017442:IPR013656:IPR010822; KEGG: cyj:Cyan7822_1383 putative PAS/PAC sensor protein; PFAM: Sporulation stage II, protein E C-terminal; GAF; Serine/threonine-protein kinase-like domain; PAS fold-4; SMART: Protein phosphatase 2C-like; GAF; Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; Tetratricopeptide repeat; [...]
  
 
 0.665
Your Current Organism:
Pseudanabaena sp. PCC7367
NCBI taxonomy Id: 82654
Other names: Calotaxis gracile PCC 7367, P. sp. PCC 7367, Pseudanabaena PCC7367, Pseudanabaena sp. PCC 7367
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.