node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFP99142.1 | SFQ22514.1 | SAMN04488506_0207 | SAMN04488506_1061 | Nucleoside diphosphate kinase; Belongs to the NDK family. | SSU ribosomal protein S1P. | 0.597 |
SFP99142.1 | guaA | SAMN04488506_0207 | SAMN04488506_0202 | Nucleoside diphosphate kinase; Belongs to the NDK family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.606 |
SFP99142.1 | guaB | SAMN04488506_0207 | SAMN04488506_1413 | Nucleoside diphosphate kinase; Belongs to the NDK family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.622 |
SFP99142.1 | rph | SAMN04488506_0207 | SAMN04488506_0777 | Nucleoside diphosphate kinase; Belongs to the NDK family. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.968 |
SFP99142.1 | rpsD | SAMN04488506_0207 | SAMN04488506_0590 | Nucleoside diphosphate kinase; Belongs to the NDK family. | Small subunit ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.660 |
SFQ14841.1 | murI | SAMN04488506_0776 | SAMN04488506_0778 | Hypothetical protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.703 |
SFQ14841.1 | rph | SAMN04488506_0776 | SAMN04488506_0777 | Hypothetical protein. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.973 |
SFQ22514.1 | SFP99142.1 | SAMN04488506_1061 | SAMN04488506_0207 | SSU ribosomal protein S1P. | Nucleoside diphosphate kinase; Belongs to the NDK family. | 0.597 |
SFQ22514.1 | guaA | SAMN04488506_1061 | SAMN04488506_0202 | SSU ribosomal protein S1P. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.721 |
SFQ22514.1 | guaB | SAMN04488506_1061 | SAMN04488506_1413 | SSU ribosomal protein S1P. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.544 |
SFQ22514.1 | rnr | SAMN04488506_1061 | SAMN04488506_1567 | SSU ribosomal protein S1P. | RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.653 |
SFQ22514.1 | rph | SAMN04488506_1061 | SAMN04488506_0777 | SSU ribosomal protein S1P. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.944 |
SFQ22514.1 | rpsD | SAMN04488506_1061 | SAMN04488506_0590 | SSU ribosomal protein S1P. | Small subunit ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.999 |
guaA | SFP99142.1 | SAMN04488506_0202 | SAMN04488506_0207 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Nucleoside diphosphate kinase; Belongs to the NDK family. | 0.606 |
guaA | SFQ22514.1 | SAMN04488506_0202 | SAMN04488506_1061 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | SSU ribosomal protein S1P. | 0.721 |
guaA | guaB | SAMN04488506_0202 | SAMN04488506_1413 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | guaC | SAMN04488506_0202 | SAMN04488506_1291 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.999 |
guaA | murI | SAMN04488506_0202 | SAMN04488506_0778 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.910 |
guaA | rph | SAMN04488506_0202 | SAMN04488506_0777 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.975 |
guaA | rpsD | SAMN04488506_0202 | SAMN04488506_0590 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Small subunit ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.893 |