STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
paaIacyl-CoA thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)    
Predicted Functional Partners:
hmp_1
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.963
paaC
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.947
paaB
phenylacetate-CoA oxygenase; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.943
PaaG
enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.942
PaaD
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.936
paaA
ATPase AAA; With PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.931
paaK
phenylacetate--CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).
 
  
 0.908
paaH_2
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.901
boxD_2
enoyl-CoA hydratase; Catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.873
paaX
Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.867
Your Current Organism:
Serratia plymuthica
NCBI taxonomy Id: 82996
Other names: ATCC 183, Bacterium plymuthicum, CCUG 14509, CIP 103239, DSM 4540, LMG 7886, LMG:7886, NBRC 102599, NCTC 12961, S. plymuthica, Serratia sp. DBLH13
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