Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANO02503.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.702
ANO02159.1
Secretion protein EspR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.689
ANO02920.1
DUF4873 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.671
ANO04938.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.668
ANO06057.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.631
ANO02510.1
Secretion protein EspR; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.591
ANO02977.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.586
ANO05880.1
Heparin-binding hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.584
ANO06813.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.573
ANO03979.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.565
Your Current Organism:
Mycobacteroides immunogenum
NCBI taxonomy Id: 83262
Other names: ATCC 700505, CCUG 47286, DSM 45595, JCM 12691, M. immunogenum, MC 779, Mycobacterium immunogenum, Mycobacterium immunogenum Wilson et al. 2001, Mycobacteroides immunogenum (Wilson et al. 2001) Gupta et al. 2018, strain BH29
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