node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANO03033.1 | ANO03341.1 | BAB75_06145 | BAB75_08020 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.921 |
ANO03033.1 | ANO04168.1 | BAB75_06145 | BAB75_12985 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
ANO03033.1 | ANO05534.1 | BAB75_06145 | BAB75_21240 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
ANO03033.1 | ANO06685.1 | BAB75_06145 | BAB75_03205 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.908 |
ANO03033.1 | era | BAB75_06145 | BAB75_09040 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTPase Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.614 |
ANO03033.1 | guaA | BAB75_06145 | BAB75_21230 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.903 |
ANO03033.1 | guaB | BAB75_06145 | BAB75_21245 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.908 |
ANO03033.1 | lysA | BAB75_06145 | BAB75_06135 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.668 |
ANO03033.1 | mfd | BAB75_06145 | BAB75_06140 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.916 |
ANO03033.1 | ndk | BAB75_06145 | BAB75_08720 | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
ANO03341.1 | ANO03033.1 | BAB75_08020 | BAB75_06145 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
ANO03341.1 | ANO04168.1 | BAB75_08020 | BAB75_12985 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.937 |
ANO03341.1 | ANO05534.1 | BAB75_08020 | BAB75_21240 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.925 |
ANO03341.1 | ANO06685.1 | BAB75_08020 | BAB75_03205 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.912 |
ANO03341.1 | guaA | BAB75_08020 | BAB75_21230 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.978 |
ANO03341.1 | guaB | BAB75_08020 | BAB75_21245 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.938 |
ANO03341.1 | ndk | BAB75_08020 | BAB75_08720 | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.939 |
ANO04168.1 | ANO03033.1 | BAB75_12985 | BAB75_06145 | Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.903 |
ANO04168.1 | ANO03341.1 | BAB75_12985 | BAB75_08020 | Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.937 |
ANO04168.1 | ANO05534.1 | BAB75_12985 | BAB75_21240 | Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.959 |