close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANO04761.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)    
Predicted Functional Partners:
ANO07075.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.804
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.796
ANO04762.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.783
ANO04895.1
Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.679
ANO02406.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.601
ANO04764.1
Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.580
ANO03782.1
Cytochrome C oxidase subunit IV; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family.
  
     0.569
ANO05758.1
Alkyl hydroperoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.520
ANO03787.1
Menaquinol-cytochrome C reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.495
ANO04894.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.435
Your Current Organism:
Mycobacteroides immunogenum
NCBI taxonomy Id: 83262
Other names: ATCC 700505, CCUG 47286, DSM 45595, JCM 12691, M. immunogenum, MC 779, Mycobacterium immunogenum, Mycobacterium immunogenum Wilson et al. 2001, Mycobacteroides immunogenum (Wilson et al. 2001) Gupta et al. 2018, strain BH29
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.