STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMS38947.1Thiamine biosynthesis protein ThiF; Pfam:pfam00899 ThiF family. (252 aa)    
Predicted Functional Partners:
AMS42862.1
Cysteine desulfarase; Pfam:pfam00266 Aminotransferase class-V.
 
 
 0.954
AMS43409.1
Molybdenum cofactor biosynthesis protein MoaE; Pfam:pfam02391 MoaE protein.
 
 0.952
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.945
AMS40618.1
Hypothetical protein; Pfam:pfam02597 ThiS family.
  
 
 0.942
AMS43410.1
Molybdenum cofactor biosynthesis protein MoaD; Pfam:pfam02597 ThiS family.
  
 
 0.869
AMS40615.1
Pfam:pfam08543 Phosphomethylpyrimidine kinase.
 
  
 0.846
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.820
AMS38950.1
Pfam:pfam01989 Protein of unknown function DUF126.
  
    0.815
AMS38948.1
Hypothetical protein; Pfam:pfam00583 Acetyltransferase (GNAT) family.
       0.804
AMS38949.1
Pfam:pfam04412 Protein of unknown function (DUF521).
       0.802
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.