close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa)    
Predicted Functional Partners:
icl
Pfam:pfam00463 Isocitrate lyase family.
 
 
 0.985
AMS39462.1
Malic enzyme; Pfam:pfam01515 Phosphate acetyl/butaryl transferase.
  
 
 0.973
AMS42802.1
Malic enzyme; Pfam:pfam01515 Phosphate acetyl/butaryl transferase.
  
 
 0.973
AMS41509.1
Hypothetical protein; Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.950
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.949
AMS40708.1
AMP-dependent synthetase; Pfam:pfam00501 AMP-binding enzyme.
  
 0.949
AMS41510.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.948
AMS42729.1
Pfam:pfam00285 Citrate synthase; Belongs to the citrate synthase family.
  
 0.948
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 0.930
AMS44055.1
2-hydroxy-acid oxidase; Pfam:pfam02754 Cysteine-rich domain.
  
 
 0.923
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
Server load: medium (76%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.