STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMS39120.1Acyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme. (422 aa)    
Predicted Functional Partners:
AMS39122.1
3-dehydroshikimate dehydratase; Pfam:pfam01261 Xylose isomerase-like TIM barrel.
 
 
  0.994
AMS39119.1
Rhizobactin siderophore biosynthesis protein RhsF; Pfam:pfam04183 IucA / IucC family.
   
 0.987
AMS39121.1
Phosphopantetheine-binding protein.
  
 0.983
AMS39118.1
Siderophore synthetase component; Pfam:pfam04183 IucA / IucC family.
 
   
 0.934
AMS43691.1
Ligase; Pfam:pfam00501 AMP-binding enzyme.
  
     0.708
AMS44230.1
Pfam:pfam02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
 
 0.649
AMS39125.1
Hypothetical protein; Pfam:pfam01032 FecCD transport family; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
     0.620
AMS39126.1
Hypothetical protein; Pfam:pfam00005 ABC transporter.
 
     0.616
AMS41485.1
AMP-dependent synthetase and ligase; Pfam:pfam00501 AMP-binding enzyme.
 
   
 0.601
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 0.598
Your Current Organism:
Aminobacter aminovorans
NCBI taxonomy Id: 83263
Other names: A. aminovorans, ATCC 23314, ATCC 29600, Aminobacter heintzii, CCUG 2081, CIP 106737, Chelatobacter heintzii, DSM 10368, DSM 7048, JCM 7852, KCTC 2477, LMG 2122, LMG:2122, NCCB 26039, NCIB 9039, NCIB:9039, NCIMB 9039, NCTC 10684, Pseudomonas aminovorans, VKM B-2058
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